Table 1 Association of polycystic ovary syndrome with pregnancy outcomes
From: Systematic review and meta-analysis of pregnancy outcomes in women with polycystic ovary syndrome
Outcome | N. studies | Effect size [95% CI] | I2 |
|---|---|---|---|
Gestational weight gain (kg) | 16 | MD 0.96 [0.01, 1.90] | 88.1% |
Post ART pregnancies | 1 | MD −1.10 [−2.53, 0.33] | .% |
Prospective design | 6 | MD 1.30 [0.27, 2.33] | 82.3% |
High quality | 3 | MD 3.24 [−0.72,7.20] | 93.3% |
Agea matched | 7 | MD 2.16 [−0.19, 4.50] | 90.8% |
BMIb matched | 4 | MD 3.10 [−0.77, 6.98] | 93.1% |
Miscarriage | 44 | OR 1.49 [1.20, 1.85] | 82.8% |
Post ART pregnancies | 29 | OR 1.23 [1.02, 1.49] | 64.2% |
Prospective design | 19 | OR 1.81 [1.22, 2.69] | 74.6% |
High quality | 6 | OR 3.38 [2.03, 5.64] | 44.8% |
Age matched | 7 | OR 3.62 [2.47, 5.29] | 0.0% |
BMI matched | 6 | OR 3.63 [2.47, 5.32] | 0.0% |
Gestational diabetes | 55 | OR 2.41 [1.95, 2.99] | 81.9% |
Post ART pregnancies | 9 | OR 1.70 [1.03, 2.80] | 82.9% |
Prospective design | 17 | OR 4.08 [2.61, 6.40] | 76.3% |
High quality | 7 | OR 2.62 [1.13, 6.07] | 87.1% |
Age matched | 14 | OR 2.05 [1.27, 3.31] | 52.4% |
BMI matched | 7 | OR 2.85 [1.41, 5.78] | 60.5% |
Gestational hypertension | 39 | OR 2.20 [1.82, 2.67] | 53.3% |
Post ART pregnancies | 4 | OR 1.84 [1.18, 2.85] | 0.0% |
Prospective design | 15 | OR 2.39 [1.72, 3.31] | 39.3% |
High quality | 9 | OR 2.19 [1.32, 3.64] | 41.4% |
Age matched | 12 | OR 2.54 [1.73, 3.73] | 0.0% |
BMI matched | 7 | OR 2.41 [1.37, 4.26] | 8.5% |
Pre-eclampsia | 34 | OR 2.30 [1.88, 2.82] | 28.1% |
Post ART pregnancies | 2 | OR 3.06 [1.01, 9.25] | 0.0% |
Prospective design | 14 | OR 2.73[1.90, 3.92] | 41.0% |
High quality | 6 | OR 3.05 [1.20, 7.80] | 51.3% |
Age matched | 10 | OR 2.81 [1.47, 5.36] | 33.8% |
BMI matched | 7 | OR 2.39 [1.14, 4.99] | 39.5% |
Eclampsia | 1 | OR 1.16 [0.44, 3.08] | .% |
Post ART pregnancies | 1 | OR 1.16 [0.44, 3.08] | .% |
Prospective design | 0 | – | – |
High quality | 0 | – | – |
Age matched | 1 | OR 1.16 [0.44, 3.08] | .% |
BMI matched | 0 | – | – |
Induction of labor | 8 | OR 1.62 [0.97, 2.70] | 81.0% |
Post ART pregnancies | 0 | – | – |
Prospective design | 5 | OR 1.67 [1.10, 2.54] | 71.4% |
High quality | 1 | OR 1.25 [0.56, 2.77] | .% |
Age matched | 1 | OR 1.25 [0.56, 2.77] | .% |
BMI matched | 1 | OR 1.25 [0.56, 2.77] | .% |
Instrumental delivery | 10 | OR 1.18 [0.91, 1.53] | 0.0% |
Post ART pregnancies | 0 | – | – |
Prospective design | 6 | OR 1.26 [0.84, 1.88] | 10.0% |
High quality | 3 | OR 0.84 [0.35, 2.04] | 13.2% |
Age matched | 4 | OR 1.02 [0.58, 1.80] | 8.2% |
BMI matched | 4 | OR 1.02 [0.58, 1.80] | 8.2% |
Cesarean section | 37 | OR 1.23 [1.06, 1.43] | 63.5% |
Post ART pregnancies | 7 | OR 0.96 [0.83, 1.12] | 3.9% |
Prospective design | 15 | OR 1.44[1.07, 1.95] | 73.5% |
High quality | 7 | OR 1.58 [1.19, 2.09] | 0.0% |
Age matched | 9 | OR 1.57 [1.24, 2.00] | 4.1% |
BMI matched | 6 | OR 1.57 [1.19, 2.07] | 0.0% |
Perinatal depression | 1 | 1.58 [0.87, 2.88] | .% |
Post ART pregnancies | 0 | – | – |
Prospective design | 0 | – | – |
High quality | 0 | – | – |
Age matched | 0 | – | – |
BMI matched | 0 | – | – |
