Table 2 Effect of maternal age, BMI and gestational weight gain on the association of maternal polycystic ovary syndrome with offspring outcomes
From: Systematic review and meta-analysis of birth outcomes in women with polycystic ovary syndrome
Outcomes | Age (year) | BMI (kg/m2) | Gestational weight gain (kg) | ||||||
|---|---|---|---|---|---|---|---|---|---|
N | Effect size | Tau2 | N | Effect size | Tau2 | N | Effect size | Tau2 | |
Preterm birth | |||||||||
MD [95%CI] | 32 | −0.49 [−0.85, −0.13] | – | 28 | 1.71 [1.23, 2.20] | – | 11 | 0.86 [−0.14, 1.86] | – |
Univariate coefficient (95% CI) | 33 | 0.16 [−0.02, 0.34] | 0.13 | 28 | 0.11 [−0.02, 0.24] | 0.14 | 11 | 0.11 [−0.17, 0.39] | 0.10 |
Birthweight (g) | |||||||||
MD [95%CI] | 33 | −0.45 [−0.84, −0.054] | – | 30 | 1.52 [0.87, 2.16] | – | 12 | 1.32 [0.16, 2.47] | – |
Univariate coefficient (95% CI) | 33 | −0.01 [−0.21, 0.19] | 0.03 | 30 | 0.04 [−0.09, 0.17] | 0.03 | 12 | −0.09 [−0.20, 0.03] | 0.11 |
Low birth weight | |||||||||
MD [95%CI] | 11 | −0.40 [−1.01, 0.22] | – | 9 | 1.32 [0.73, 1.91] | – | 3 | −0.55 [−1.90, 0.80] | – |
Univariate coefficient (95% CI) | 11 | 0.24 [−0.11, 0.59] | 0.14 | Insufficient number | – | 3 | Insufficient number | – | |
Small for gestational age | |||||||||
MD [95%CI] | 15 | −0.47 [−1.06, 0.13] | – | 10 | 1.95 [0.14, 3.75] | – | 6 | 0.50 [−0.86, 1.87] | – |
Univariate coefficient (95% CI) | 15 | 0.05 [−0.23, 0.34] | 0.03 | 10 | −0.02 [−0.25, 0.21] | 0.17 | 6 | Insufficient number | – |
Macrosomia | |||||||||
MD [95%CI] | 19 | −0.25 [−0.69, 0.188] | – | 15 | 1.78 [1.17, 2.40] | 6 | 0.61 [−0.63, 1.85] | – | |
Univariate coefficient (95% CI) | 19 | −0.05 [−0.25, 0.15] | 0.07 | 15 | −0.03 [−0.22, 0.15] | 0.07 | 6 | Insufficient number | – |
