Fig. 3: Simulations of elongasome tug-of-war dynamics.
From: Molecular motor tug-of-war regulates elongasome cell wall synthesis dynamics in Bacillus subtilis
a Cartoon of elongasome complex dynamics as implemented in the stochastic model. b Illustration of the two models of elongasome tug-of-war tested: end-binding, where only one synthesis complex can bind to each end of the antiparallel MreB double filament, in opposite directions; unlimited binding, where multiple synthesis complexes can bind along the MreB filament. c, d Examples of simulated elongasome dynamics at low (10−2 arb. Units), intermediate (100 arb. Units) and high (102 arb. Units) synthesis complex (synthase) concentrations for end-binding and unlimited binding models. e–g Fraction of motile elongasomes, their processivity and reversal rate as a function of synthesis complex concentration for both models. Solid coloured lines with filled circles, sample medians; vertical lines, 95% CI. Number of simulation replicates for each condition, 100. Further quantification in Supplementary Fig. 13.
