Fig. 6: Mechanism investigations. | Nature Communications

Fig. 6: Mechanism investigations.

From: Chemo-, regio- and stereoselective access to polysubstituted 1,3-dienes via Nickel-catalyzed four-component reactions

Fig. 6

a In the control experiments, metal catalysis, ligand, and base are essential for this catalytic cycle. b Radical inhibition reactions using TEMPO. c Radical trapping reactions using 1,1-Diphenylethylene. d Standard reaction condition using Ni(II) complex. dtbpy = 4,4′-di-tert-butyl-2,2′-dipyridyl. e To explore the role of PCy3. a Yields were determined by gas chromatography (GC) using n-dodecane as the internal standard. TEMPO = 2,2,6,6-tetramethylpiperidinyloxy, PCy3 = tricyclohexyl phosphine, DMA = N, N-dimethylacetamide, DME = 1,2-dimethoxyethane.

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