Fig. 1: Scheme of DNA hydrogel band-aid for accelerated hemostasis that can fulfill the clinical requirements of stabilizing a profuse bleeding wound.
From: Neutrophil extracellular traps-inspired DNA hydrogel for wound hemostatic adjuvant
Physiologically, neutrophils at the wound site released extracellular DNA to form traps (NETs) that promote fast and stable thrombosis. Similarly, our form factor conforming DNA hydrogel was able to form NETs-like thrombosis. Besides the conformational advantage, DNAgel is also highly absorptive of blood at the wound edge and high adhesive to the wetted wound surfaces, thus forming both a physical blockade and biological clot to stop the bleeding.
