Fig. 4: Predicted loss-of-function copy-number variation associated with uRPL.
From: Common and rare genetic variants predisposing females to unexplained recurrent pregnancy loss
a A quantile–quantile plot of the P-values of tested genes from the pLoF CNV burden test. The gray diagonal dashed line is the identity line. The pink horizontal dashed line indicates the Bonferroni-corrected significance threshold of α = 0.05. Detailed association results are available in Supplementary Data 2. All statistical tests are two-sided and unadjusted for multiple comparisons. b Locations of the CDH11 pLoF CNVs in the uRPL cases are shown.
