Table 1 Basic clinical characteristics of the IBD patients and healthy controls

From: Therapeutic potential of the secreted Kazal-type serine protease inhibitor SPINK4 in colitis

 

N

UC

CD with classical therapy

CD with anti-TNF-α therapy

N

64

51

43

65

Male, n (%)

33 (51.6)

28 (54.9)

22 (51.2)

41 (63.1)

Median age, yr, (IQR)

25 (24–28)

42 (35–56)

28 (25–36)

25 (19.75–31.25)

BMI,kg/m2, (IQR)

-

19.6 (18.4–23.8)

18.7 (16.8–20.5)

19.4 (17.7–21.0)

Disease phenotype, n (%)

  L1

-

-

11 (25.6)

7 (10.8)

  L2

-

-

0 (0)

3 (4.6)

  L3

-

-

30 (69.8)

55 (84.6)

  L4

-

-

2 (4.7)

0 (0)

  B1

-

-

19 (44.2)

34 (52.3)

  B1p

-

-

7 (16.3)

16 (24.6)

  B2

-

-

7 (16.3)

24 (36.9)

  B2p

-

-

2 (4.7)

7 (10.8)

  B3

-

-

17 (39.5)

7 (10.8)

  B3p

-

-

8 (18.6)

5 (7.7)

  p

-

-

17 (39.5)

28 (43.1)

Disease extent, n (%)

  Proctosigmoiditis

 

5 (9.8)

-

-

  Left‐sided colitis

 

14 (27.5)

-

-

  Pancolitis

 

32 (62.7)

-

-