Fig. 4: Therapeutic apheresis for a sensitized mouse recipient to treat transplant rejection via the ATAS. | Nature Communications

Fig. 4: Therapeutic apheresis for a sensitized mouse recipient to treat transplant rejection via the ATAS.

From: Acoustofluidic-based therapeutic apheresis system

Fig. 4

a and b Schematic of treatment procedure for allogeneic skin graft transplanted mouse recipient by reducing the donor-specific antibody (DSA) level in the recipient’s blood to reduce transplant rejection. c Photographs of the tubing of the ATAS and the connection via vein catheters. d DSA level testing for the sample collected from the plasma outlet and cell outlet of the ATAS. e and f Serum DSA level testing for the recipient animals’ pre- and post-apheresis. Data represent the mean ± SD; n  =  4. The statistical analysis was performed using a two-sided Student’s t-test. Data are graphed as the mean ± SD. Source data are provided as a Source Data file. Figure a, b created with BioRender.com.

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