Fig. 5: Neural results: a priori higher-level pain processing ROIs. | Nature Communications

Fig. 5: Neural results: a priori higher-level pain processing ROIs.

From: Placebo treatment affects brain systems related to affective and cognitive processes, but not nociceptive pain

Fig. 5

The mean signal across all voxels of each a priori ROI across participants are presented, in the Control (red) and Placebo (blue) condition, for each combination of modality and stimulus level. Error bars represent within-participant standard error of the mean, based on Morey, 2008107. N = 392 participants. Asterisks represent significance of the placebo effect (mixed-effects model, uncorrected): *p < 0.05, **p < 0.01, ***p < 0.001. For additional visualizations see Supplementary Fig. 7. L left, R right, dlPFC dorsolateral prefrontal cortex, OFC orbitofrontal cortex, NAc nucleus accumbens.

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