Table 1 Statistics for a priori nociceptive ROIs: stimulus level effect

From: Placebo treatment affects brain systems related to affective and cognitive processes, but not nociceptive pain

Region

Modality

Estimate

95% CI

SE

t

DF

p value

aMCC

Thermal

0.166

[0.084, 0.249]

0.042

3.97

763.9

<0.001

Mechanical

0.128

[0.049, 0.208]

0.040

3.18

461.9

0.002

dpIns L

Thermal

0.091

[0.013, 0.169]

0.040

2.29

589.2

0.023

Mechanical

0.067

[āˆ’0.012, 0.147]

0.041

1.66

750.9

0.098

dpIns R

Thermal

0.116

[0.038, 0.195]

0.040

2.90

966.5

0.004

Mechanical

0.125

[0.048, 0.203]

0.039

3.18

871.8

0.002

PAG

Thermal

0.102

[0.016, 0.189]

0.044

2.33

1296.6

0.020

Mechanical

0.157

[0.070, 0.244]

0.044

3.56

369.1

<0.001

Med Thal

Thermal

0.064

[āˆ’0.016, 0.144]

0.041

1.58

537.2

0.115

Mechanical

0.077

[āˆ’0.003, 0.158]

0.041

1.90

498.0

0.058

VPL/M Thal L

Thermal

0.059

[āˆ’0.016, 0.134]

0.038

1.55

1056.0

0.121

Mechanical

0.019

[āˆ’0.062, 0.101]

0.041

0.47

341.7

0.637

VPL/M Thal R

Thermal

0.076

[āˆ’0.007, 0.159]

0.042

1.81

675.7

0.072

Mechanical

0.038

[āˆ’0.042, 0.118]

0.041

0.94

1076.3

0.350

  1. Full statistics for the mixed effects models of the activity in each a priori ROI, for the stimulus level effect. Significant p values (uncorrected pā€‰<ā€‰0.05) are marked in bold.
  2. CI confidence interval, DF degrees of freedom, L left, R right, aMCC anterior midcingulate cortex, dpIns dorsal posterior insula, Med Thal medial thalamus, VPL/M Thal ventral posterior thalamus, PAG periaqueductal gray.
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