Table 3 Statistics for a priori ROIs for higher-level pain processing: stimulus level effect

From: Placebo treatment affects brain systems related to affective and cognitive processes, but not nociceptive pain

Region

Modality

Estimate

95% CI

SE

t

DF

p value

dlPFC L 1

Thermal

āˆ’0.008

[āˆ’0.089, 0.072]

0.041

āˆ’0.20

594.6

0.840

Mechanical

0.017

[āˆ’0.065, 0.098]

0.042

0.40

1242.5

0.689

dlPFC L 2

Thermal

0.077

[āˆ’0.005, 0.159]

0.042

1.85

758.5

0.065

Mechanical

0.088

[0.008, 0.169]

0.041

2.16

487.3

0.031

dlPFC R

Thermal

āˆ’0.001

[āˆ’0.084, 0.081]

0.042

āˆ’0.04

553.6

0.972

Mechanical

āˆ’0.019

[āˆ’0.103, 0.065]

0.043

āˆ’0.44

462.4

0.658

Lateral OFC

Thermal

āˆ’0.027

[āˆ’0.107, 0.053]

0.041

āˆ’0.67

616.0

0.505

Mechanical

āˆ’0.040

[āˆ’0.122, 0.043]

0.042

āˆ’0.95

929.8

0.345

Anterior OFC 1

Thermal

āˆ’0.052

[āˆ’0.131, 0.027]

0.040

āˆ’1.30

539.2

0.194

Mechanical

āˆ’0.018

[āˆ’0.103, 0.067]

0.043

āˆ’0.42

1246.8

0.674

Anterior OFC 2

Thermal

āˆ’0.002

[āˆ’0.086, 0.081]

0.043

āˆ’0.05

689.1

0.961

Mechanical

0.039

[āˆ’0.045, 0.123]

0.043

0.91

657.2

0.362

Mid-lateral OFC L

Thermal

āˆ’0.020

[āˆ’0.098, 0.059]

0.040

āˆ’0.49

1132.8

0.623

Mechanical

0.02

[āˆ’0.069, 0.110]

0.046

0.45

628.7

0.655

Mid-lateral OFC R

Thermal

āˆ’0.003

[āˆ’0.083, 0.077]

0.041

āˆ’0.07

647.5

0.948

Mechanical

0.045

[āˆ’0.041, 0.132]

0.044

1.03

583.3

0.303

NAc L

Thermal

āˆ’0.011

[āˆ’0.094, 0.071]

0.042

āˆ’0.27

1370.7

0.785

Mechanical

0.123

[0.038, 0.208]

0.043

2.84

1211.7

0.005

NAc R

Thermal

0.074

[āˆ’0.004, 0.152]

0.040

1.85

660.9

0.064

Mechanical

0.071

[āˆ’0.013, 0.154]

0.042

1.67

647.6

0.096

  1. Full statistics for the mixed effects models of the activity in each a priori higher-level pain processing ROI, for the stimulus level effect. Significant p values (uncorrected pā€‰<ā€‰0.05) are marked in bold.
  2. CI confidence interval, DF degrees of freedom, L left, R right, dlPFC dorsolateral prefrontal cortex, OFC orbitofrontal cortex, NAc nucleus accumbens.
Back to article page