Fig. 4: The associations between differential metabolites and cardiovascular events. | Nature Communications

Fig. 4: The associations between differential metabolites and cardiovascular events.

From: Plasma metabolomics reveals the shared and distinct metabolic disturbances associated with cardiovascular events in coronary artery disease

Fig. 4

The forest plot showed the ORs (95% CI) of differential metabolites with the composite (n = 332) and individual events (Cardiovascular death: n = 242; Heart failure: n = 208; MI/stroke: n = 259) in the validation set. Only differential metabolites both showed significant association with cardiovascular events in discovery set and validation set after adjusting for TIMI variables, hs-cTnT, and NT-proBNP were exhibited in the figure. The measure of centre for the error bars presented the ORs of differential metabolites, the dash line demonstrated the 95% CI of ORs after adjusting for TIMI variables, while the solid line showed the 95% CI of ORs after adjusting for TIMI variables, hs-cTnT, and NT-proBNP. hs-cTnT high sensitivity cardiac troponin T; LPC lysophosphatidylcholine; NT-proBNP N-terminal pro-brain natriuretic peptide; OR odds ratio; PC phosphatidylcholine; TIMI Thrombolysis In Myocardial Infarction.

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