Fig. 4: Expanding scope to 1,1-disubstituted allene.
From: Regioselective fluorination of allenes enabled by I(I)/I(III) catalysis
Reaction conditions: allene (0.1 mmol), catalyst (30 mol%), amine•HF (0.25 mL), DCM (0.25 mL) and Selectfluor® (0.2 mmol). Isolated yields reported. a 19F NMR yield using ethyl fluoroacetate as internal standard. b Reaction time increased to 48 h. The enantiomer of the product shown was arbitrarily shown.
