Fig. 4: Association of transthyretin levels with outcomes.

This figure depicts a forest plot summarizing the association of transthyretin (TTR) levels and the study outcomes [heart failure, cardiovascular disease (composite of heart failure, stroke, and coronary heart disease), atherosclerotic cardiovascular disease (composite of stroke and coronary heart disease), all-cause mortality, and cardiovascular mortality among 35,206 individuals. Cox models, adjusted for age, sex, Townsend index, BMI, SBP, total cholesterol, diabetes, smoking status, eGFR, statin use, and antihypertensive use, were used to examine the association of TTR levels and the study outcomes. The hazard ratio and 95% confidence interval per SD decrease in TTR levels have been depicted.