Fig. 5: MAP-kinase pathway driver mutations tend to arise after tumor initiation. | Nature Communications

Fig. 5: MAP-kinase pathway driver mutations tend to arise after tumor initiation.

From: The genetic evolution of acral melanoma

Fig. 5

NRAS mutations (a), NF1 mutations (b), CIC homozygous deletion (c), PTPN11 mutation (d), and KIT mutations (e) arose after tumor initiation in multiple acral melanomas, placing them on the respective branches of the corresponding phylogenetic trees.

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