Fig. 5: Gene modules of ErbB family. | Nature Communications

Fig. 5: Gene modules of ErbB family.

From: CGMega: explainable graph neural network framework with attention mechanisms for cancer gene module dissection

Fig. 5

a Illustrations show the gene modules of the ErbB family. Blue dots indicate query genes, namely ERBB1, ERBB2, ERBB3 and ERBB4. Yellow dots indicate genes located at the center of gene modules. Green boxes show the RFs of query genes. b Feature importance scores of the ErbB family. c The high-order gene module formed by the ErbB family gene modules. d Hypothetical model of the high-order gene module formed by the ErbB family gene modules in maintaining protein phosphorylation homeostasis. Details were described in the main text. Source data are provided as a Source Data file.

Back to article page