Table 1 Cohort characteristics of preterm infants analyzed in this study

From: Prolonged hospitalization signature and early antibiotic effects on the nasopharyngeal resistome in preterm infants

NP cohort

Naive

Early-antibiotics

p

n

21

15

 

Male, n (%)

12 (57%)

11 (73%)

0.484

GA, weeks (mean, SD)

31, 6/7

29 5/7, 1

<0.001

BW, grams (mean, SD)

1562, 188

1306, 277

<0.05 (0.0022)

BW, group, n (%)

  

<0.05 (0.013)

 ELBW

0 (0%)

2 (13%)

 

 VLBW

8 (38%)

10 (67%)

 

 LBW

13 (62%)

3 (20%)

 

Mode of delivery, n (%)

  

0.694

 Vaginal

4 (19%)

4 (27%)

 

 C-section

17 (81%)

11 (73%)

 

Antibiotics during pregnancy, n (%)

  

<0.001

 None

21 (100%)

6 (40%)

 

 <10 days

0

7 (47%)

 

 >= 10 days

0

2 (13%)

 

Intrapartum antibiotics (IAP), n (%)

  

0.50

 None documented

2 (10%)

0 (0%)

 

 Given

19 (90%)

15 (100%)

 

ROM, hours (mean, SD)

3, 12

432, 733

<0.05 (0.0108)

Apgar10 (mean, SD)

9, 1

8, 1

0.3039

Nutrition (discharge to 6 months CA)

  

<0.05 (0.039)

 Fully breastfed

7 (33%)

4 (29%)

 

 At least 50% mother milk, but also some formula

3 (14%)

6 (42%)

 

 Mostly formula and some mothers milk

6 (29%)

0 (0%)

 

 Formula

2 (10%)

4 (29%)

 

Lost to follow-up

3 (14%)

1 (7%)

0.626

  1. Baseline characteristics are represented as counts (n) and percentages (%) for categorical variables, and mean and standard deviation (SD) for continuous variables. Pearson’s chi-squared test or Fisher’s exact test was used for categorical variables, and a two-sided unpaired t-test was used for continuous variables to calculate differences between groups (p < 0.05). P-values (p) written in bold indicate nominally significant differences between groups.