Fig. 2: Single-cell RNAseq analysis identifies transcriptional NK cell subsets. | Nature Communications

Fig. 2: Single-cell RNAseq analysis identifies transcriptional NK cell subsets.

From: Single-cell profiling identifies a CD8bright CD244bright Natural Killer cell subset that reflects disease activity in HLA-A29-positive birdshot chorioretinopathy

Fig. 2

A UMAP plot of 306,425 PBMCs from 12 birdshot uveitis patients (BCR-UV) and 12 healthy controls (HC). The identified lineage clusters are highlighted (color-coded). B Dot plot showing the expression profile of NK surface marker-encoding genes across the annotated cell clusters identified in A. C UMAP plots of NK cells gated from the C4_Natural Killer cells cluster in A comparing NK subclusters in BCR-UV and HC. The 12 transcriptional NK cell subclusters are color-coded. D Dot plot showing the expression profile of NK surface marker encoding genes in each of the subclusters as identified in C.

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