Fig. 3: Direct and indirect effects of healthy lifestyle, and association of pre-infection medical conditions with multisystem sequelae of COVID-19. | Nature Communications

Fig. 3: Direct and indirect effects of healthy lifestyle, and association of pre-infection medical conditions with multisystem sequelae of COVID-19.

From: Modifiable lifestyle factors and the risk of post-COVID-19 multisystem sequelae, hospitalization, and death

Fig. 3

a Proportion of the direct and indirect effect of a healthy lifestyle on multisystem sequelae (intermediate/favorable vs unfavorable lifestyle). Direct associations were accounted for pre-infection medical conditions (mediator), identified as any relevant event recorded between baseline measurement and infection date. b Association of corresponding pre-infection medical conditions with the risk of sequelae following SARS-CoV-2 infection. Outcomes were ascertained 0–210 days after SARS-CoV-2 infection. The horizontal bars indicate HR and lines indicate 95% CIs. The sample size was 68,892. 7975 incident events for any sequela, 354 for general fatigue, 923 for coagulation diseases, 1938 for neurologic diseases, 800 for pulmonary diseases, 2023 for Kidney diseases, 2064 for gastrointestinal diseases, 1739 for mental disorders, 1895 for musculoskeletal diseases, 2077 for cardiovascular diseases, and 2152 for diabetes.

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