Table 2 Association of composite healthy lifestyle with multisystem sequelae, death, and hospitalization following SARS-CoV-2 infection in key clinical subgroups

 < 65

0.74 (0.64–0.85)

0.08

<0.001

0.58 (0.39–0.85)

0.06

0.01

0.86 (0.76–0.96)

0.47

0.03

0.51 (0.44–0.59)

0.39 (0.25–0.61)

0.69 (0.61–0.78)

 ≥ 65

0.84 (0.76–0.93)

0.77 (0.68–0.88)

0.88 (0.81–0.97)

0.70 (0.64–0.78)

0.61 (0.54–0.70)

0.83 (0.76–0.91)

Female

0.78 (0.69–0.89)

0.30

0.02

0.63 (0.51–0.78)

0.04

0.09

0.82 (0.73–0.92)

0.42

0.14

0.58 (0.51–0.67)

0.52 (0.42–0.64)

0.73 (0.65–0.81)

Male

0.80 (0.72–0.89)

0.81 (0.70–0.93)

0.90 (0.82–0.99)

0.69 (0.61–0.77)

0.62 (0.53–0.73)

0.83 (0.75–0.91)

White

0.75 (0.69–0.82)

0.01

<0.001

0.74 (0.65–0.85)

0.67

0.36

0.84 (0.78–0.90)

00.04

<0.001

0.59 (0.54–0.64)

0.58 (0.50–0.67)

0.73 (0.68–0.79)

Other ethnic groups

1.10 (0.86–1.42)

0.78 (0.61–1.01)

1.01 (0.81–1.25)

0.93 (0.72–1.21)

0.65 (0.50–0.85)

1.02 (0.82–1.27)

No or partial vaccination

0.88 (0.78–0.99)

0.13

0.21

0.85 (0.74–0.98)

0.02

0.04

0.89 (0.80–0.99)

0.63

0.19

0.72 (0.63–0.81)

0.69 (0.60–0.80)

0.78 (0.70–0.87)

Full vaccination

0.75 (0.67–0.84)

0.62 (0.49–0.79)

0.86 (0.78–0.95)

0.60 (0.53–0.67)

0.53 (0.41–0.68)

0.79 (0.72–0.87)

Inpatient

0.80 (0.73–0.88)

0.91

0.42

0.80 (0.67–0.96)

0.87

0.33

0.89 (0.82-–0.97)

0.07

0.13

0.64 (0.58–0.70)

0.64 (0.53–0.77)

0.80 (0.74–0.87)

Community/outpatient

0.83 (0.70–0.99)

0.78 (0.66–0.92)

0.81 (0.68–0.95)

0.75 (0.63–0.90)

0.69 (0.58–0.83)

0.81 (0.68–0.96)

Wildtype, alpha, and delta

0.76 (0.69–0.84)

0.07

0.27

0.77 (0.68–0.88)

0.56

0.44

0.80 (0.73–0.87)

0.01

0.06

0.63 (0.57–0.70)

0.60 (0.53–0.69)

0.76 (0.69–0.83)

Omicron BA.1

0.94 (0.80–1.09)

0.70 (0.51–0.95)

1.05 (0.92–1.20)

0.72 (0.61–0.84)

0.69 (0.51–0.95)

0.89 (0.78–1.01)