Table 3 Minimum inhibitory concentration (MIC) values of library DMxiPeny(x:y) against clinically isolated drug-resistant bacterial
From: AI-guided few-shot inverse design of HDP-mimicking polymers against drug-resistant bacteria
Strain | MIC(μg mL−1) | |||||
---|---|---|---|---|---|---|
10:0 | 9:1 | 8:2 | 7:3 | 6:4 | 5:5 | |
Staphylococcus aureus USA300 | 25 | 12.5 | 12.5 | 12.5 | 12.5 | 12.5 |
Staphylococcus aureus MU50 | 25 | 12.5 | 12.5 | 12.5 | 12.5 | 25 |
Staphylococcus aureus Newman | 50 | 25 | 12.5 | 12.5 | 12.5 | 50 |
Staphylococcus aureus R02 | 25 | 12.5 | 12.5 | 12.5 | 12.5 | 25 |
Staphylococcus aureus R03 | 25 | 25 | 12.5 | 12.5 | 12.5 | 25 |
Vancomycin resistant enterococcus-1 | 12.5 | 6.25 | 6.25 | 6.25 | 6.25 | 12.5 |
Vancomycin resistant enterococcus-2 | 12.5 | 6.25 | 6.25 | 6.25 | 6.25 | 12.5 |
Escherichia coli JM109 | 25 | 12.5 | 12.5 | 12.5 | 12.5 | 25 |
Escherichia coli R19 | 50 | 25 | 12.5 | 12.5 | 12.5 | 25 |
Pseudomonas aeruginosa R09 | 12.5 | 6.25 | 6.25 | 6.25 | 6.25 | 25 |
Pseudomonas aeruginosa R10 | 12.5 | 12.5 | 6.25 | 6.25 | 6.25 | 25 |