Fig. 3: The detailed interactions of ASB7 with LZTS1-degron.
From: Molecular insights into degron recognition by CRL5ASB7 ubiquitin ligase
a–d Close-up view of the interactions of E1, E8, L5, L12, and L16 in degron site 1 (yelloworange) with ASB7 (palegreen). The hydrogen bonds are shown as black dashed lines. e, f Close-up view of the interactions of L2, Q9, and E13 in site 2 with ASB7. g Interactions of K15 in site3 with ASB7. h Interactions of the extended Y19 of the LZTS1-degron with ASB7. i Schematic of the detailed interactions between ASB7 proteins and LZTS1-degron. Dashed lines and arrows indicate hydrogen bonds and hydrophobic interactions, respectively.
