Fig. 2: Trans-located caRNAs are particularly enriched at TAD boundaries.
From: Exploring the roles of RNAs in chromatin architecture using deep learning
a The percentage of HFFc6 TAD boundaries located in A and B compartments. b Chromatin accessibility (ATAC-seq, left panel), and the abundance of nascent transcripts (middle panel) and trans-located caRNAs (right panel) at TAD boundaries (center) and their flanking regions in HFFc6. c Chromatin accessibility, the abundance of nascent transcripts and trans-located caRNAs, and the abundance of trans-located caRNAs normalized to chromatin accessibility, at strong (n = 7175) versus weak (n = 3971) TAD boundaries. The center line and triangle within the box represent the median and mean value, respectively. The box represents the interquartile range (IQR), with whiskers set to 1.5 times the IQR. Outliers are shown in points. Two-sided Mann-Whitney U tests were used to evaluate the differences between strong and weak TAD boundaries. U statistics and p-values are shown in the plot. Source data are provided as a Source Data file.
