Fig. 6: Scope of kinetic resolution reactions. | Nature Communications

Fig. 6: Scope of kinetic resolution reactions.

From: Chemo-, regio- and enantioselective hydroformylation of trisubstituted cyclopropenes: access to chiral quaternary cyclopropanes

Fig. 6

All reactions were performed on 0.2 mmol in 1 mL toluene with 1 mol % Rh(acac)(CO)2 and 2 mol % ligand under 2.5/2.5 bar (CO/H2) at 60 °C for 10 h. Isolated yield. Ee was determined by HPLC analysis using a chiral stationary phase. aPerformed at CO/H2 = 1/1 bar, 60 °C for 12 h. s = ln[(1 − conv)(1 − ee1)]/ln[(1 − conv)(1 + ee1)], conv = ee1/(ee1 + ee2).

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