Fig. 1: Workflow of the study.

MS multiple sclerosis, PPMS primary progressive MS, SPMS secondary progressive MS, RRMS relapsing-remitting MS, SNP single nucleotide polymorphism, meQTL and eQTL methylation and expression quantitative trait loci, SWE Swedish cohort, ITA Italian cohort, META meta-analysis of the SWE and ITA cohorts.