Fig. 2: Integration of scRNA-seq and spatial transcriptomic data of the CCS.
From: Transcriptional regulation of the postnatal cardiac conduction system heterogeneity
a CCS-specific enriched genes for each CCS component identified by both scRNA-seq and spatial transcriptomics. b Molecular gradients within the CCS components showing zonated enrichment of genes in Nodal cells (SA node, Compact AV node), Lower nodal bundle & Proximal VCS (His bundle, Proximal bundle branch), and Distal VCS (Distal bundle branch, Purkinje fibers). LBB left bundle branch, RBB right bundle branch, RAA right atrial appendage, LENDO left ventricular endo-myocardium, LEPI left ventricular epi-myocardium, IVS-B interventricular septum (Base), IVS-A interventricular septum (Apex), RV right ventricle, VCS ventricular conduction system.
