Fig. 3: The structural transition of TM7.
From: Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2
a The changes in torsional angle observed over the trajectory run in GltTk. Close-ups represent the starting conformation, in which TM7 is in the compact form (yellow) found in substrate-bound states (lower left), and the final conformation with an extended TM7 (orange; upper right). b The distribution of torsional angle observed in the simulation of GltTk as seen in (a). c, The changes in torsional angle observed over the trajectory run in ASCT2. Close-up represents the starting conformation, in which TM7 is in the compact form (yellow), maintained throughout the entire simulation time (lower right). d The distribution of torsional angle observed in the simulation of ASCT2 as seen in (c).
