Fig. 6: Intracerebral inflammation in live animals using 124I-DPA-713 PET/CT. | Nature Communications

Fig. 6: Intracerebral inflammation in live animals using 124I-DPA-713 PET/CT.

From: Dynamic PET reveals compartmentalized brain and lung tissue antibiotic exposures of tuberculosis drugs

Fig. 6

Mice underwent live imaging two weeks after treatment initiation. a Transverse 124I-DPA-713 PET/CT images of representative mice from different treatment regimens and untreated mice. b Quantification of 124I-DPA-713 PET signal in the brain represented as standard uptake value mean (SUVmean) (animal numbers, n = 8/untreated, 4/Pa100SMx, 4/BPa50L, 4/BPa50LZ, 4/Pa50LMxZ, and 4/Pa100LZ) are shown. Data are represented as median ± interquartile range. Statistical comparisons were made using a two-tailed Mann-Whitney U test. Source data are provided as a Source Data file.

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