Fig. 4: Gain and loss of anaerobic enzymes and MRO proteins over the tree of Metamonada.
From: Extreme mitochondrial reduction in a novel group of free-living metamonads
Gains (red) and losses (blue) of key metabolic pathway components discussed throughout this paper are mapped on a schematic phylogeny of Metamonada (based on Fig. 1). Protein abbreviations are: HydG/E/F Iron hydrogenase maturase G/E/F, ACS Acetyl-CoA synthase, NuoE/F Respiratory-chain NADH dehydrogenase 24/51 kDa subunit, GCS Glycine cleavage system, SCS Succinyl-CoA synthase, IscS/U Iron-sulfur cluster assembly enzyme system. The Spironucleus ACS is denoted as ACS* as an ACS “type” could not be confidently assigned.
