Fig. 5: Longitudinal assessment of FcγRs interaction with post-MARV infection plasma. | Nature Communications

Fig. 5: Longitudinal assessment of FcγRs interaction with post-MARV infection plasma.

From: Longitudinal proteome-wide antibody profiling in Marburg virus survivors identifies wing domain immunogen for vaccine design

Fig. 5

Quantification of FcγRI, FcγRIIA, FcγRIIIA, FcγRIIB, or FcγRIIIB interaction with longitudinal 10 MVD survivor plasma antibodies from 12 to 60 months post-infection bound to MARV VLP (recombinant VLPs expressing MARV trimeric GP on the surface of particles made of MARV matrix proteins VP40 and NP) coupled beads using the bead-based assay. The level of binding is shown as mean fluorescent intensity (MFI). Each sample was run in duplicate, and each dot represents an average of duplicate values. The variation for each sample in duplicate runs was <5%. Source data are provided as a Source Data file.

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