Fig. 1: ASCA separation of IgG antibody profiles by vaccine recipient. | Nature Communications

Fig. 1: ASCA separation of IgG antibody profiles by vaccine recipient.

From: Profiling IgG and IgA antibody responses during vaccination and infection in a high-risk gonorrhoea population

Fig. 1

In the left-hand panels, each point represents a profile derived from IgG reactivity against antigens across the array. Comp 1 and Comp 2 represent the first and second principal components in the ASCA analysis. Confidence ellipsoids are plotted that reflect the estimated variation of the effect level means at 40, 68 and 95%22. Open symbols represent individual serum samples; ellipsoid centres are plotted as filled symbols. Righthand panels show the antigens with the highest loadings for each component. A ASCA calculation with all antigens included. B As A but with NHBA, Factor H binding protein (fHbp), GNA2091 and GNA1030 removed.

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