Fig. 2: Aging induces higher glucose uptake in unstimulated B cells.
From: Immunometabolic effects of lactate on humoral immunity in healthy individuals of different ages
B cells, isolated as in Fig. 1, were left unstimulated. a mRNA expression of the glucose transporter Glut1 measured by qPCR. Results show qPCR values (2−ΔCt), mean ± SE. b Representative flow cytometry histograms from one young and one elderly individual of glucose uptake measured by flow cytometry using the glucose fluorescent analog 2-NBDG. Results show MFI (mean fluorescence intensity). c 2-NBDG MFI results from all individuals, mean ± SE. Source data are provided as a Source Data file. Mean comparisons between groups were performed by unpaired Student’s t test (two-tailed). ****p < 0.0001.
