Fig. 3: Offspring haplotypes from zpg−7280/N’Gousso hybrid females, pools A-C. | Nature Communications

Fig. 3: Offspring haplotypes from zpg−7280/N’Gousso hybrid females, pools A-C.

From: Homing gene drives can transfer rapidly between Anopheles gambiae strains with minimal carryover of flanking sequences

Fig. 3

Haplotypes of offspring from parents A-C (see Supplementary Table 1) showing gene conversion tracts (GCTs) generated during gene drive homing based on presence and absence of SNPs present between the parent chromosomes (represented above each graph). The relative proportion of each haplotype is given as well as a description of the haplotype. Black lines represent a SNP present in the gene drive donor (G3) chromosome of the parent and absent in the recipient (N’Gousso) chromosome. Regions between a present and absent SNP are labelled as ambiguous, as gene conversion may have ended at any point in this region. Alleles present at <10% relative abundance after filtering are shown with narrow bars, as they may be either a sequencing artifact or a minor homed allele. *proportions are inaccurate due to the presence of a SNP in the binding site of the primer used to amplify the genomic sequence on the donor chromosome. Figure 3 was created with BioRender.com released under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International license (https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en).

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