Fig. 5: Offspring haplotypes from vas2−5958/N’Gousso hybrid parents, pools G-L. | Nature Communications

Fig. 5: Offspring haplotypes from vas2−5958/N’Gousso hybrid parents, pools G-L.

From: Homing gene drives can transfer rapidly between Anopheles gambiae strains with minimal carryover of flanking sequences

Fig. 5

Haplotypes of offspring from parents G, H, K and L (see Supplementary Table 1) showing gene conversion tracts (GCTs) generated during gene drive homing. Due to the use of males mated en masse in vas2−5958 crosses the gene drive parent could not be sequenced; therefore, classification of haplotypes as from donor or recipient chromosomes are based on the assumption that the most abundant haplotype in each vas2-5958 matches the donor chromosome of the parent. Black lines represent a SNP present in the donor (G3) chromosome and absent in the recipient (N’Gousso) chromosome. Regions between a present and absent SNP are labelled as ambiguous, as gene conversion may have ended at any point in this region. Alleles present at <10% relative abundance after filtering are shown with narrow bars, as they may be either a sequencing artifact or a minor homed allele. Figure 5 was created with BioRender.com released under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International license (https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en).

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