Fig. 3: Scope of cyclic amine-derived ureas. | Nature Communications

Fig. 3: Scope of cyclic amine-derived ureas.

From: Site-selective α-C(sp3)–H arylation of dialkylamines via hydrogen atom transfer catalysis-enabled radical aryl migration

Fig. 3

Reaction conditions: urea (0.2 mmol), 4-DPAIPN (2 mol%), iPr3SiSH (30 mol%) and Na2CO3 (2.5 equiv.) in CH3CN (0.1 M) at room temperature for 24 h under 450 nm blue LED light irradiation. Site- and diastereo-selectivity were recorded by 1H and 2D NMR spectroscopy analysis. Isolated yields. If not specified, the products are obtained with >99:1 site-selective ratios.

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