Table 2 EI-52 quantification in the tumor using LCMS/MS

From: Targeting ERK-MYD88 interaction leads to ERK dysregulation and immunogenic cancer cell death

Treatment

Concentration (ng/g)

Tumor weight (g)

Total qty (ng)

Vehicle

BLQ

0.95

BLQ

Vehicle

BLQ

1.13

BLQ

Vehicle

BLQ

1.30

BLQ

Vehicle

BLQ

1.41

BLQ

EI-52

407.10

1.05

426.93

EI-52

240.09

0.83

198.27

EI-52

440.67

0.55

241.88

EI-52

355.71

1.48

52.09

  1. BLQ: Below the limit of quantitation, i.e. <6 ng/g