Fig. 1: The proposed biosynthetic pathway of CC in Apiaceae.
From: The gradual establishment of complex coumarin biosynthetic pathway in Apiaceae
PAL phenylalanine ammonia lyase, C4H cinnamate 4-hydroxylase, 4CL 4-coumarate: coenzyme A ligase, HCT/HQT hydroxycinnamoyl CoA shikimate/quinate hydroxycinnamoyl transferase, CCoAOMT caffeoyl-CoA O-methyltransferase, C3’H cinnamoyl ester 3’-hydroxylase, C2’H p-coumaroyl CoA 2’ -hydroxylase, F6’H feruloyl-CoA 6’-hydroxylase, COSY coumarin synthase, U6PT umbelliferone 6-prenyltransferase, U8PT umbelliferone 8-prenyltransferase, DC demelthyisuberosin cyclase, OC osthenol cyclase. The plant in the picture is the newly sequenced P. praeruptorum rich in all coumarin types and particularly high angular CC content.
