Fig. 7: The biosynthetic gene cluster of CCs in P. praeruptorum and A. sinensis.
From: The gradual establishment of complex coumarin biosynthetic pathway in Apiaceae
PpC2’Hs, PpPTs and PpOC are located in a gene cluster of Chromosome 9 in the P. praeruptorum genome, while PpDC is located in Chromosome 7, not belonging to the gene cluster. Multiple rounds of tandem duplications involving PpC2’Hs and PpPTs can be recognized according to the gene phylogenies. A. sinensis has a similar gene cluster with containing C2’H, C-PT and cylcase in a collinear genomic block to that of P. praeruptorum.
