Fig. 2: AB25583 acts synergistically with Olaparib. | Nature Communications

Fig. 2: AB25583 acts synergistically with Olaparib.

From: Structural basis for a Polθ helicase small-molecule inhibitor revealed by cryo-EM

Fig. 2

a, b Scatter plot showing % colony survival of PE01 cells (a) and MDA-MB-436 cells (b) in the presence of the indicated concentrations of Olaparib and AB25583 or DMSO (left). Data represent the mean of two biological replicates performed in triplicate ±s.e.m. Plots generated by Combenefit software showing synergy between AB25583 and Olaparib (right). Source data are provided as a Source data file.

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