Fig. 5: Analysis of substitution rate variability.
From: High-resolution epidemiological landscape from ~290,000 SARS-CoV-2 genomes from Denmark

Regression coefficients of a model incorporating all four factors to estimate (a) substitution rate using ordinary least squares (OLS) (without interaction between factors) and (b) the number of substitutions using zero-inflated negative binomial regression (without interaction between factors). Groups where the confidence interval does not cross zero (dashed line) indicates significant difference from the reference group. Data are presented as mean ± 95% confidence intervals; n = 289,072 with full metadata for all covariates.