Fig. 3: Post-burst responses exhibit diverse patterns including response facilitation and habituation.
From: Theta-burst direct electrical stimulation remodels human brain networks
A K-means clusters of within-train post-burst responses (n = 65 channels with significant within-train responses). Cluster 1 showed an increasing post-burst response, cluster 2 a decrease in post-burst response, cluster 3 an initial increase and subsequent decrease. B Amongst channels with significant within-train plasticity, 60% were in cluster 1, 26% in cluster 2 and 18% in cluster 3. C K-means clustering criterion did not converge at an optimal cluster number for across-train plasticity dynamics. Up-trending and down-trending post-burst responses were identified by comparing the first two trains and the last two trains (n = 239 channels with significant across-train responses). D 21% of channels with plasticity had a positive trend, 13% had a negative trend, and 66% had a trend that did not differ in initial and final post-burst responses. Error bars reflect the standard error of the mean.
