Fig. 8: Structural, resting and effective connectivity at rest predict sites of TBS-evoked responses and plasticity.

A Receiver Operating Characteristic (ROC) curves derived from baseline characteristics used to predict presence of a significant TBS post-burst response at a given channel. The curves are further stratified by channels either closer than or further from 30 mm of the stimulation site. B The mean T-statistic for baseline features used in models to construct the ROC curves. Note CCEP amplitude is the most significant predictor for TBS+ channels (n = 20 model runs, 10-fold cross-validation per each distance cutoff). C ROC curves for prediction of plasticity using only TBS+ channels. D The mean T-statistic for baseline features used in models to construct the ROC curves. Note distance to the stimulation site is the most significant predictor for channels with plasticity (n = 20 model runs, 10-fold cross-validation per each distance cutoff). E ROC curves for prediction of types of plasticity using only channels that demonstrated plasticity. F The mean T-statistic for baseline features used in models to construct the ROC curves. Note CCEP amplitude is the most significant predictor for type of plasticity (n = 20 model runs, 10-fold cross-validation per each distance cutoff). Error bars represent +/− SEM.