Fig. 2: Temporal disease patterns in the clusters according to UKB (N = 502,504). | Nature Communications

Fig. 2: Temporal disease patterns in the clusters according to UKB (N = 502,504).

From: Unique genetic and risk-factor profiles in clusters of major depressive disorder-related multimorbidity trajectories

Fig. 2

A The average onset ages of the most prevalent (>5%) cross-cohort diseases (per line) according to the seven clusters in the UKB cohort. The node colour indicates the clusters, and the node size is proportional to the observed prevalence of the disease (in %) in the cluster. MDD is highlighted with red colour. B The onset distribution of all cross-cohort diseases in the clusters of the UKB cohort is shown as violin plots, where the colour indicates the cluster. Each of the seven violin plots represents one cluster, computed using data from the entire cohort (N = 502,504), with individuals weighted by their posterior probability of belonging to the respective cluster. The onset distribution and the mean age of MDD onset are indicated with inline red violin plots and red vertical bars, respectively.

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