Fig. 4: Structural change and conformational type vs accuracy.
From: Structure prediction of alternative protein conformations
a Structural change and accuracy. The x-axis shows the TM-score difference between the native conformations and the y-axis is the TM-score for the prediction and the structure of the test confirmation. The Pearson R is −0.62, suggesting that there is a relationship between the structural change and accuracy and that structures that change more between their conformations are harder to predict. The points represent each structure (n = 155) and the line is the running average using a step size of 0.02 TM-score. b Conformational type and accuracy. The hinge motions are less accurately predicted than the rearrangements and fold switches. This is likely explained by the findings in (a).
