Fig. 8: Effects of BmOSER1 and Ceoser1 on reproduction.
From: FOXO-regulated OSER1 reduces oxidative stress and extends lifespan in multiple species

a Representative images of eggs laid by wildtype (oeCtrl) and BmOSER1 overexpression (oeBmOSER1) silkworms. As shown, one male silkworm mates with 6 females in the wildtype Dazao and produces hatchable eggs, while in BmOSER1 overexpression silkworms, one male mates with 23 females that laid hatchable eggs. b Duration of the entire fertile mating period between male and female adult silkworms. c Number of successful matings per male adult silkworms. d The number of eggs laid per female adult silkworms in wildtype and BmOSER1 knockout. e–f The total brood sizes of Ceoser1 RNAi (Ceoser1 RNAi) (e) and overexpression (oeCeoser) (f) throughout life. Data in all scatter plots are presented as mean with SD and analyzed by Unpaired t-test, Two-tailed. n.s., not significant; **p < 0.01, ***p < 0.001, ****p < 0.0001. All data points derive from independent silkworms or nematodes. Source data are provided as a Source Data file.