Fig. 3: Application and performance of scDist.
From: Robust identification of perturbed cell types in single-cell RNA-seq data

A Reanalysis of the data from Fig. 1A using distances calculated with scDist; the dashed red line represents ground truth value of 0. B As in A, but for p-values computed with scDist; values above the dashed red line represent p < 0.05. C Null simulation from Fig. 1C reanalyzed using distances calculated by scDist; the dashed red line represents the ground truth value of 0. Points and error bands represent the mean  ±1 SD. D Dendrogram generated by hierarchical clustering based on distances between pairs of cell types estimated by scDist. In all panels the boxplots display median and first/third quartiles. Source data are provided as a Source Data file.