Fig. 6: Different TIR defense systems can recognize different components of the same phage.
From: The role of TIR domain-containing proteins in bacterial defense against phages
a–c Plaque assays showed the resistance of different escaped phages of #117 (a), #45 (b), and #70 (c) from different systems. The escaped phages can only escape the TIR system, from which they were selected. The empty vector lacking the TIR system was used as a negative control. d Toxicity assays of the tail tube protein of phage #117 in the presence of the Thoeris-II, TIR-III, or TIR-VII systems. e Toxicity assays of the ssDNA-binding protein (SSB) of phage #45 in the presence of the TIR-Retron, TIR-I, or TIR-IV systems. Protein expression was induced by the addition of arabinose. The empty vector lacking the TIR system was used as a negative control. Source data are provided as a Source data file.
