Fig. 5: The movement of TM1 and TM6 and the role Trp56.
From: Molecular basis of inhibition of the amino acid transporter B0AT1 (SLC6A19)
A comparison is drawn between the apo structure of B0AT1 (PDB: 6M18) when bound with JX225 (a) and JX98 (b), respectively. The apo structure of B0AT1 is shown in green, while the ligand-bound structures are shown in orange (JX225) and pink (JX98). The alterations in the positions of TM1 and TM6 are depicted in the middle and right panels. JX225 (a) and JX98 (b) are represented in coral and magenta, respectively.
