Fig. 8: In vivo anti-tumor effect in BALB/c mice. | Nature Communications

Fig. 8: In vivo anti-tumor effect in BALB/c mice.

From: A singular plasmonic-thermoelectric hollow nanostructure inducing apoptosis and cuproptosis for catalytic cancer therapy

Fig. 8

a Therapeutic schedule of Cu2−xSe HNSs for CT26 tumor-bearing mice. b Biodistribution of Cu in major organs and tumors after tail vein injection of Cu2−xSe HNSs solution at different time intervals (% injectable dose (ID) of Cu per gram of tissue, n = 3 biologically independent samples). c Assessment of hemolysis of erythrocytes by Cu2−xSe HNSs in distilled water (DW) (n = 5 biologically independent data). d–e Tumor temperature change curves (d) and corresponding infrared thermal images (e) obtained under 1064 nm irradiation after injection of PBS and Cu2−xSe HNSs in mice. f The PA images of the tumor area after tail vein injection of Cu2−xSe HNSs at different time points. g–k Tumor volume (g, h), a photograph of the dissected tumor (i), tumor weight (j), and H&E-stained photographs of tumor slices after various treatments (k). Scale bar for k: 50 μm. Data presented as mean ± S.D. (n = 5 mice). Source data are provided as a Source Data file.

Back to article page