Fig. 6: Genetic differentiation of GmSW17 in soybean germplasm and a proposed working model of GmSW17 in controlling seed size in soybean.
From: Natural variation in GmSW17 controls seed size in soybean
a Haplotype frequency distribution of GmSW17 among wild soybeans (n = 88 accessions), landraces (n = 858 accessions), and improved cultivars (n = 1123 accessions). b π values associated with GmSW17 in wild soybeans, landraces and improved cultivars. c FST values associated with GmSW17 in wild soybeans, landraces and improved cultivars. The thresholds of FST(Soja_Landrace), FST(Landrace_Cultivar) are 0.702 and 0.089, respectively. The red dotted line represents GmSW17, and the dark dotted lines represent the other genes. d A proposed model elucidating the role of GmSW17 in regulating seed size in soybean. GmSW17, GmSGF11 and GmENY2 form a trimeric DUB module that functions to reduce H2Bub levels in soybean. As GmSW17H2 has a stronger enzymatic activity in deubiquitinating H2Bub than GmSW17H1, the H2Bub level of GmDP-E2F-1 decreased, resulting in lower expression levels of GmDP-E2F-1. Consequently, the constraint on the G1 to S phase transition was alleviated, ultimately leading to increased seed size.
